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The most important difference between phenylephrine (PE) and pseudoephedrine (PDE) is that the efficacy as PE as a decongestant is unproven, …Phenylephrine is a direct-acting sympathomimetic amine that functions as an alpha-1 adrenergic agonist. Its chemical structure is related to epinephrine and ephedrine and possesses potent vasoconstriction properties when given intravenously or applied directly to mucosal membranes.The F.D.A. will make its own decision on whether to remove medications containing the ingredient, phenylephrine, which is found in products like Sudafed P.E., NyQuil Severe Cold & Flu and Tylenol ...People may sometimes confuse pseudoephedrine with phenylephrine, which is an over-the-counter (OTC) medication with similar brand names, such as Sudafed PE. In this article, we look at how alcohol ...Gently pat yourself dry with a towel. Fiber supplements. These reduce hemorrhoid bleeding, inflammation, and enlargement by drawing water into your stool to make it easier to pass. A psyllium husk fiber supplement, such as Metamucil or a generic equivalent, is a good choice, although psyllium may cause gas or bloating.Interestingly, this is largely attributed to the meth control laws enacted across the US in the late 90s early 2000s. Biker here have to deal with blister packs, while barrels of chinese pseudoephedrine are still (relatively) easy to come by south of the border. We choked off the local supply, and outsourced the production.Sep 13, 2023 · Popular nasal decongestant doesn't actually relieve congestion, FDA advisers say The FDA asked advisers to take another look at phenylephrine, which became the main drug in over-the-counter ... Ticoll B and Shugar G. have reported that fully related these effects to a 41-year old patient suffering from paranoid psychosis as the result of use of nasal oxymetazoline spray [12]. Snow SS. has reported the addition to phenylephrine in a 26-year old patient which actually resulted in toxic psychosis [13].nearest store had no benzedrex, so i got Neo-Synephrine nasal spray. didn't realize it contained "phenylephrine 0.5%" and it's a liquid, not cotton. has anyone had a good experience consuming this? or is there no way to get similar effects to propylhexedrine from it and i should just keep looking for benzedrex?Phenylephrine is a pure alpha-adrenergic agonist and is considered the sympathomimetic agent of choice for treatment of ischemic priapism by the American Urological Association (AUA) and Sexual Medicine Society of North America (SMSNA) due to its rapid onset and short duration of action. 2 Compared with other sympathomimetic medications ... Even 120 mg, twice the medical dose, has significant nice effects. There is a mood lift with a greater appreciation of the present, due to I guess an improved ability to focus on the present. My body feels light and movement feels easier. Higher doses make the mood lift even more impressive, but also become rushy.Well, phenylephrine is metabolized by MAO, so going with a much lower dose would be a good idea if you did take it. There are reports in the literature of patients taking selegiline and amphetamine, combined with a beta-blocker for hypertensive side effects. Granted that's a selective MAOI, but combining MAOIs and stimulants isn't an automatic ...Phenylephrine is a type of nasal decongestant in over-the-counter (OTC) medications, such as Sudafed PE. Phenylephrine is available as a standalone medication, or as part of a multidrug ...Phenylephrine is a medication used as a decongestant for uncomplicated nasal congestion, [3] used to dilate the pupil, used to increase blood pressure (given intravenously in cases of hypotension ), and used to relieve hemorrhoids. [2] [4] It is a selective α 1 -adrenergic receptor agonist with minimal to no beta-adrenergic activity. [3]Phenylephrine : r/depression • 12 yr. ago by coolgherm Phenylephrine Does anybody know about using phenylephrine as an antidepressant. I have had a cold for the last two weeks and have been taking dayquil to combat the mucus. It has phenylephrine in it. For the last few days of taking it, I have felt better than I have in years. I just discovered a wicked legal phenylalanine high. Just hold any drink with phenylalanine added under the tongue for about 15-30 seconds and you'll be halfway to mars faster than major tom with the help of ground control. Very likely endorphin system based.Medicated decongestant spray like Afrin works pretty well if you use it correctly. Give each nostral a nice coating (1 or 2 pumps) every twelve hours and it won't lose its effectiveness until after 4 or 5 days.Yes i am aware of the side effects. No i do not really mind them they are better then falling asleep at my desk. (And i’ve read you can get a bit of a high out of em too. 😁) It's a terrible "decongestant" and causes migraines for many people. Not much of a stim.oral phenylephrine is ineffective as a decongestant, Other examples of scientifically proven ineffective OTC medications include guaifenesin as an expectorant, …Evidence of phenylephrine's effectiveness comes from a review that combined and analyzed the results of seven individual studies. It found the drug had a small but real effect on nasal airway ... If it's medicated with some sort of decongestant (Sudafed/pseudoephedrine, phenylephrine, etc), again, it should work pretty much immediately. If it's medicated with a steroid (Flonase, Nasacort, etc), however, these can take a few days to work. They're basically artificial hormones that tell your body to stop swelling up.FDA held a Non-prescription Drug Advisory Committee meeting Sept. 11-12, 2023, to discuss the effectiveness of oral phenylephrine as an active ingredient in over-the-counter (OTC) cough and cold ...4 comments [deleted] • 5 yr. ago Phenylephrine works as a vasoconstrictor, which raises BP and heart rate. Probably why its associated with an increased risk of …

This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are now allowed as responses to this comment. Phenylephrine is recognized as the preferred agent of choice even though use in the context of acute ischemic priapism is off label. The AUA/SMSNA provided evidence to support the use of phenylephrine over other sympathomimetic agents. Phenylephrine has been compared to other agents, including epinephrine and ethylephrine, and was found …15 votes, 24 comments. Making Methamphetamine at home: List of chemicals and materials: Diluted HCl - also called Muriatic acid - can be obtained…4 oct. 2023 ... ... Reddit Print Story Like. An advisory panel to the Food and Drug ... phenylephrine doesn't work to clear nasal congestion when taken orally.

2 great_site_not • 5 yr. ago You need different friends. 200mg of phenylephrine is extremely dangerous, and anyone who'd hand it to you and tell you it's fine is dangerously negligent (assuming it wasn't malicious). But phenylephrine absolutely sucks as a decongestant (which is why it is rarely sold as a solo product), and has only gained popularity since the introduction of the Combat Methamphetamine Epidemic Act of 2005 which restricted sales of the much superior decongestants, ... Reddit . reReddit: Top posts of June 23, 2022.…

Reader Q&A - also see RECOMMENDED ARTICLES & FAQs. I personally think phenylephrine is a placebo. So many people do. Possible cause: Phenylephrine may cause serious side effects. Stop using phenylephrine .