Sep 13, 2023 · Popular nasal decongestant doesn't actually relieve congestion, FDA advisers say The FDA asked advisers to take another look at phenylephrine, which became the main drug in over-the-counter ... I personally think phenylephrine is a placebo. So many people don't know any better and just keep taking Sudafed because "that's what you take" and don't even think to look at that. But it's literally never done anything for me.Lock the medicine up high, out of sight and reach of young children. If you think a child has swallowed too much cough or cold medicine, use the web POISON CONTROL ® online tool for guidance or call Poison Control at …Dilated blood vessels can cause nasal congestion (stuffy nose). Pseudoephedrine is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes. Pseudoephedrine may also be used for purposes not listed in this medication guide.The best non-prescription, safe, legal ADHD "mitigatior" that I have found is xenon. It greatly helps with meditation, is anti-anxiety, and apparently helps with exercise as well. It will not "cure" ADHD -- that is a very complex issue. It is more expensive than most nootropic pills -- but google around and find something you can affore. View community ranking In the Top 1% of largest communities on Reddit. OTC Fever/Flu meds? Hey guys, I've got a fever, bordering flu symptoms, at the moment. I know there was another thread for cold medication recently which recommended Benzablock L but it hasn't been effective. ... But it might of changed to phenylephrine.Brompheniramine And Phenylephrine (Rynex PE) received an overall rating of 0 out of 10 stars from 0 reviews. See what others have said about Brompheniramine And Phenylephrine (Rynex PE), including the effectiveness, ease of use and side eff...There’s more to life than what meets the eye. Nobody knows exactly what happens after you die, but there are a lot of theories. On Reddit, people shared supposed past-life memories that made them believe reincarnation could be possible. Do ...nearest store had no benzedrex, so i got Neo-Synephrine nasal spray. didn't realize it contained "phenylephrine 0.5%" and it's a liquid, not cotton. has anyone had a good experience consuming this? or is there no way to get similar effects to propylhexedrine from it and i should just keep looking for benzedrex?But phenylephrine absolutely sucks as a decongestant (which is why it is rarely sold as a solo product), and has only gained popularity since the introduction of the Combat Methamphetamine Epidemic Act of 2005 which restricted sales of the much superior decongestants, ... Reddit . reReddit: Top posts of June 23, 2022.Desloratadin has the lowest anticholinergic effect of all H1 antihistamines. Anticholinergic meds increase your risk for neurodegenerative disorders quite a lot. Desloratadin is according to studies even more effective than Cetirizin and it has a mild mastcell stabilising effect. Considering side and long-term effects Desloratadin is definitely ...Aug 31, 2023 · Phenylephrine is a decongestant that constricts (shrinks) dilated blood vessels within the nose, relieving congestion. Injectable forms may also be used to increase blood pressure. Phenylephrine works by directly stimulating alpha-1 adrenergic receptors in the arteries causing vasoconstriction (narrowing of the blood vessels). Horak et al 2008, Day et al and a half dozen others found Phenylephrine significantly less effective than pseudoephedrine as decongestant. As far as I know every trial comparing the pseudoephedrine and phenylephrine as a decongestant has found pseudoephedrine superior, in most cases by a large margin.Agreed. Currently I am in pharmacy school. All the literature points to that it is either ineffective or the dosing is not right. Regardless, replacing pseduoephedrine with phenylephrine has not curbed methamphetamine production. False product extentions are confusing patients.Phenylephrine nasal spray has the same 3 day use limit; and oral phenylephrine is trash. I would never recommend it. If symptoms persist beyond 3 days I’d recommend seeing a physician anyway; but they can have some pseudoephedrine in the mean time. But honestly; I’m pretty sure rebound congestion from oxymetazoline is a myth.Fischman: Today, we’re talking about decongestants. Scientists who advise the FDA recently concluded that phenylephrine, a common decongestant in cold medicines, doesn’t work. We’ll talk ...A warning about stimulants and cold medicine. In a nutshell, I was on 10 of Prozac titrating up to 20 slowly, and had just increased my dose of Vyvanse again when my asthma flaired up. I had to take my Albuterol inhaler and Robitussin with dextromethorphan and guaifenesin. I had a nightmare response that caused a crazy panic episode that lasted ... Pseudoephedrine vs phenylephrine. Studies show that phenylephrine taken orally has no better effect on nasal decongestion than nothing at all. I know in the US, we have to go to the pharmacist and ask for pseudoephedrine, but it is vastly more effective than the current regular OTC formulas. FYI - You can get 5 boxes of 24 tablets at Costco for ... Phenylephrine — the ingredient deemed ineffective — took off in popularity as a replacement for pseudoephedrine. Mike Koelzer, a pharmacist in Grand Rapids, Michigan, said he doesn’t expect any...Apr 21, 2023 · Takeaway. Pseudoephedrine and phenylephrine are both nasal decongestants but can have different side effects. You can only purchase pseudoephedrine from pharmacy staff and have to show your ID ... It wasn’t until 1976 that the F.D.A. began reviews of over-the-counter cold medicines, like phenylephrine, as a class of drugs. But by the early 1990s, the decongestant still hadn’t received a ...Don’t mix combo meds containing Sudafed and alcohol. It is also important to recognize that the active ingredient in Sudafed is often found in combination drugs used to treat cold and/or flu symptoms. These drugs typically contain medications that do have known drug-drug or drug-alcohol interactions, such as Tylenol, Advil, or Benadryl.Phenylephrine is used in a broad array of over-the-counter medications like Sudafed PE and Dimetapp. The drug brought in nearly $1.8 billion in sales in 2022, according to an FDA briefing document ...Word of advice from my own experience: While your medication is kicking in, do EVERYTHING within your power to not use your phone, watch youtube videos, browse reddit, or anything else that gives instant gratification. Because if you do, you risk spending half your day doing only that.By 2022, the FDA estimates that Americans bought 242 million phenylephrine-containing products, taking the lion's share of the decongestant market and generating nearly $1.8 billion in sales.Phenylephrine may cause serious side effects. Stop using phenylephrine and call your doctor at once if you have: fast, pounding, or irregular heartbeat; severe dizziness or nervousness; sleep problems ( insomnia ); or. increased blood pressure--severe headache, blurred vision, pounding in your neck or ears.How it works Phenylephrine is a decongestant that constricts (shrinks) dilated blood vessels within the nose, relieving congestion. Injectable forms may also be used to increase blood pressure. Phenylephrine works by directly stimulating alpha-1 adrenergic receptors in the arteries causing vasoconstriction (narrowing of the blood vessels).The effectiveness of a nootropic varies a lot from one person to another (your mileage will vary).This is why I built a nootropic recommendation system Enter ratings on nootropics you’ve tried, and it will spit out nootropics liked by people with similar rating patterns. This was initially based on the 2016 SlateStarCodex nootropics survey data., …Phenylephrine, the nasal decongestant in many cold medicines, found ineffective by FDA panel. The leading decongestant used by millions of Americans looking for relief from a stuffy nose is likely ...The phenylephrine (PE) form is no better than a placebo when taken in pill form. It only works as a decongestant when used in a liquid form on direct contact with nasal tissues. I still can't believe they actually approved the PE forms of decongestant pills. Phenylephrine is a type of nasal decongestant in over-the-counter (OTC) medications, such as Sudafed PE. Phenylephrine is available as a standalone …Research comparing phenylephrine to a placebo in the treatment of nasal congestion has yielded mixed results, with some studies showing minimal effectiveness compared to a placebo. This lack of significant difference in symptom relief has raised questions about the efficacy of phenylephrine in some cases.MAOIs are amazing antidepressants and anti-anxiety agents - in part because they work very differently compared to most other neuropharmaceuticals. MAOIs work intracellularly and compared to other ADs there is tolerance/counterregulation to that, hence much less "poop-out". However, there is a reason why MAOIs are underprescribed.Ticoll B and Shugar G. have reported that fully related these effects to a 41-year old patient suffering from paranoid psychosis as the result of use of nasal oxymetazoline spray [12]. Snow SS. has reported the addition to phenylephrine in a 26-year old patient which actually resulted in toxic psychosis [13]. The F.D.A. will make its own decision on whether to remove medications containing the ingredient, phenylephrine, which is found in products like Sudafed P.E., NyQuil Severe Cold & Flu and Tylenol ...Sudafed aka pseudoephedrine can increase anxiety. There’s also another decongestant called Phenylephrine it’s not as strong as Sudafed but it can cause anxiety as well. Eville2010 • 5 yr. ago. I took plain Mucinex without the D (decongestant). Assilem113 • 5 yr. ago.In fact, some research has found that at the current recommended doses of phenylephrine it offers minimal symptom improvement. It may be safer for people with high blood pressure and heart disease, but there is not enough research to be certain. Decongestant effects beyond the noseHey guys, I was just wondering if phenylephrine hydrochloride would clear my blocked ear. I went to the pharmacy and asked for something that would help unblock my ear, and they gave me this Maxiclear Sinus relief which contained phenylephrine hydrochloride, and I was wondering if this was effective.Brompheniramine And Phenylephrine (Rynex PE) received an overall rating of 0 out of 10 stars from 0 reviews. See what others have said about Brompheniramine And Phenylephrine (Rynex PE), including the effectiveness, ease of use and side eff...Push-dose vasopressors, or push-dose pressors, refers to administration of intermittent, small doses of vasopressors to optimize a patient’s hemodynamic status [2, 3]. Commonly used push-dose vasopressors include epinephrine and phenylephrine [2, 3]. Push-dose administration is a long standing practice amongst anesthesiologists to …But phenylephrine absolutely sucks as a decongestant (which is why it is rarely sold as a solo product), and has only gained popularity since the introduction of the Combat Methamphetamine Epidemic Act of 2005 which restricted sales of the much superior decongestants, ephedrine and pseudoephedrine (which you need to purchase from behind the ...Phenylephrine is a decongestant used to relieve nasal pressure and stuffiness often associated with a cold or allergies. It supposedly works by stimulating alpha-1 adrenergic receptors in the ...Phenylephrine is an alpha-agonist - that is, it works at "alpha receptors" in our body. The main effects of these receptors is to cause things to squeeze, like blood vessels, for example. That's how they work on congestion - squeezed vessels = less leaky. Phenylephrine mainly works on the alpha-1 receptors, and that's what their job is - squeezing.View community ranking In the Top 1% of largest communities on Reddit. FDA panel to reevaluate the most common over-the-counter decongestant, phenylephrine, criticized as useless. cbsnews ... So with phenylephrine it works on your alpha receptor to squeeze blood vessels down. This causes an increase in BP with a related slowing of the heart ...Reddit Link. view video. ... Food and Drug Administration scientists say that oral phenylephrine doesn't work for nasal decongestion, though the agency's final decision has yet to be made.Pseudoephedrine is fine. The one you gotta look out for is phenylephrine, AKA Sudafed-PE. It reacts with amphetamine-related drugs, including Adderall and meth, to cause heart problems. Always, always look up drug interactions when you're on something long-term! Interactions aren't always major or dangerous, but it's good to know about them.The federal purchase limit is 3.6 milligrams of pseudoephedrine base in a single day and nine milligrams in a single month. The monthly limit should be enough to keep you covered during allergy ...How it works Phenylephrine is a decongestant that constricts (shrinks) dilated blood vessels within the nose, relieving congestion. Injectable forms may also be used to increase blood pressure. Phenylephrine works by directly stimulating alpha-1 adrenergic receptors in the arteries causing vasoconstriction (narrowing of the blood vessels).Mar 30, 2022 · Pseudoephedrine is an adrenergic receptor ligand, but it has far less stimulating properties than methamphetamine and a better pharmacological profile than ephedrine. It is famous for drying nasal passages during colds and allergies, at which it excels. Some people still notice amphetamine-like effects of sleeplessness and jitters at those ... Phenylephrine may cause serious side effects. Stop using phenylephrine and call your doctor at once if you have: fast, pounding, or irregular heartbeat; severe dizziness or nervousness; sleep problems ( insomnia ); or. increased blood pressure--severe headache, blurred vision, pounding in your neck or ears.Agreed. Currently I am in pharmacy school. All the literature points to that it is either ineffective or the dosing is not right. Regardless, replacing pseduoephedrine with phenylephrine has not curbed methamphetamine production. False product extentions are confusing patients.18 déc. 2022 ... Tylenol Cold and Flu (acetaminophen/dextromethorphan/guaifenesin/phenylephrine); Zyrtec (cetirizine). Angina Medications. Angina (ischemic chest ...Desloratadin has the lowest anticholinergic effect of all H1 antihistamines. Anticholinergic meds increase your risk for neurodegenerative disorders quite a lot. Desloratadin is according to studies even more effective than Cetirizin and it has a mild mastcell stabilising effect. Considering side and long-term effects Desloratadin is definitely ...I recently noticed an interaction between propanol and adderall myself. This has happened a few times I will stand up after sitting for an extended period of time and I will feel light headed and fall down to the ground. It does not seem to occur if I skip the beta blocker and just take the adderall.Phenylephrine also has different side effects. It “can slightly increase people’s blood pressure or a feeling of jumpiness more than other medications,” said Dr. Robert Eitches, a Los ...It really just depends for everyone if it will give you bad side effects or not. Since you have a low tolerance to adderall, take 5mg first and see how bad the load is. If it isn't too bad, you can take more, but know that the half life of phenylephrine is about 3 hours, so it does not go away quickly. willis81808 • 9 yr. ago.It really just depends for everyone if it will give you bad side effects or not. Since you have a low tolerance to adderall, take 5mg first and see how bad the load is. If it isn't too bad, you can take more, but know that the half life of phenylephrine is about 3 hours, so it does not go away quickly. willis81808 • 9 yr. ago.Horak et al 2008, Day et al and a half dozen others found Phenylephrine significantly less effective than pseudoephedrine as decongestant. As far as I know every trial comparing the pseudoephedrine and phenylephrine as a decongestant has found pseudoephedrine superior, in most cases by a large margin. Reddit; Print; By Tina Hesman Saey. April 30, 2020 at 5:36 pm. Scientists are investigating a variety of drugs, including ones for anxiety and allergies, that might prevent the coronavirus from ...25 avr. 2023 ... Note that either pseudoephedrine or phenylephrine can be found in cough/cold formulations, allergy and asthma medications, hemorrhoid creams, ...Fischman: Today, we're talking about decongestants. Scientists who advise the FDA recently concluded that phenylephrine, a common decongestant in cold medicines, doesn't work. We'll talk ...Fascinating story behind that. Guaifenesin was an unapproved drug not long ago. Was in common use before the FDA came around, so it was “grandfathered”. However the FDA provided an incentive for any company who submitted it for approval - 5 years of market exclusivity. So a private equity firm shelled out a bunch of money, a company was ...First step is to remove the top part (may need to be pried off, the seam is pretty tight and hard to see), and then empty the bottle of the saline. Next, you'll need to crush up and add your coke to the bottle. I use one gram of high quality cocaine per bottle, but you could make it less or more potent.I just discovered a wicked legal phenylalanine high. Just hold any drink with phenylalanine added under the tongue for about 15-30 seconds and you'll be halfway to mars faster than major tom with the help of ground control. Very likely endorphin system based.Phenylephrine was approved by the FDA for over-the-counter use in the 1970s, but it became even more common after 2005, when legislation restricted access to OTC drugs that use a similar ...Phenylephrine is a vasoconstrictor - which reduces sinus congestion by shrinking capillaries and veins. Also, from Wikipedia: Phenylephrine is marketed as an alternative for the decongestant pseudoephedrine, although clinical trials show phenylephrine, taken orally at the recommended dose, to be no more effective than placebo for allergy relief. On Tuesday, a U.S. Food and Drug Administration advisory committee voted unanimously that the oral formulation of a very common nasal decongestant, phenylephrine, is not effective. The decision ...Gently pat yourself dry with a towel. Fiber supplements. These reduce hemorrhoid bleeding, inflammation, and enlargement by drawing water into your stool to make it easier to pass. A psyllium husk fiber supplement, such as Metamucil or a generic equivalent, is a good choice, although psyllium may cause gas or bloating.People may sometimes confuse pseudoephedrine with phenylephrine, which is an over-the-counter (OTC) medication with similar brand names, such as Sudafed PE. In this article, we look at how alcohol ...I just discovered a wicked legal phenylalanine high. Just hold any drink with phenylalanine added under the tongue for about 15-30 seconds and you'll be halfway to mars faster than major tom with the help of ground control. Very likely endorphin system based. The amount of fluids infused during the study period in the phenylephrine and norepinephrine groups was similar (2,554 ± 1,140 ml versus 2,431 ± 1,010 ml, P = 0.751). Phenylephrine dosages were higher than those for norepinephrine 12 hours after randomization (P < 0.001) (Figure (Figure2). 2). The goal MAP of 65 to 75 mmHg was …But it's in nearly every food you eat - meat, fish, nuts, cheeses, Pepsi Max, so on and so forth. Now, phenylalanine can be dangerous, if you lack a certain enzyme that converts it to a compound called tyrosine. If you lack this enzyme, then you have a disease called phenylketonuria. Judging by the fact that you don't know what phenylalanine ...This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are now allowed as responses to this comment.Phenylephrine : r/depression • 12 yr. ago by coolgherm Phenylephrine Does anybody know about using phenylephrine as an antidepressant. I have had a cold for the last two weeks and have been taking dayquil to combat the mucus. It has phenylephrine in it. For the last few days of taking it, I have felt better than I have in years. 17 jan. 2023 ... Acetaminophen, the same painkiller that's found in Tylenol. Phenylephrine, a decongestant that can relieve a stuffy nose caused by allergies, ...I agree with you. In pretty much every situation a human would consume aspartame, it is totally and completely harmless. There have been studies that showed problems, but they require such insane doses of aspartame in such a short period of time that they're ridiculous.19 fév. 2010 ... Pseudoephedrine is found in Sudafed, as well as many combination products. Phenylephrine is the only other oral nasal decongestant known to be ...Phenylephrine. Phenylephrine is a widely used vasopressor in the operating room for the treatment of hypotension. The primary binding target of phenylephrine is the α-adrenergic receptor with the highest affinity for the α1 -receptor. Phenylephrine is an α 1 selective agonist but may affect β-receptors in high doses.2 great_site_not • 5 yr. ago You need different friends. 200mg of phenylephrine is extremely dangerous, and anyone who'd hand it to you and tell you it's fine is dangerously negligent (assuming it wasn't malicious). r/phenylephrine: A community dedicated to the medicinal or recreational use of the alpha-adrenergic receptor agonist phenylephrine. Chemistry … 19 fév. 2010 ... Pseudoephedrine is found in Sudafed, as well as many combination products. Phenylephrine is the only other oral nasal decongestant known to be ...According to Healthline, the phenylephrine in Preparation H “may temporarily make the area around the eyes appear tighter.”. However, applying the cream around the eye area can have unwanted side effects. According to the Mayo Clinic, hydrocortisone can cause a “thinning, weakness, or wasting away of the skin.”.Other pharmacists have expressed concerns over phenylephrine's effectiveness as a nasal decongestant,[1] and other clinicians have indicated concern for regulatory actions that reduced the availability of pseudoephedrine.[12][13] A subsequent meta-analysis by the same researchers concluded that there is insufficient evidence for its ...13 sept. 2023 ... 11-12 to decide if the drug phenylephrine should continue to be sold as a treatment for nasal decongestion. ... Reddit; Copy Link to Blog Post.But phenylephrine absolutely sucks as a decongestant (which is why it is rarely sold as a solo product), and has only gained popularity since the introduction of the Combat Methamphetamine Epidemic Act of 2005 which restricted sales of the much superior decongestants, ephedrine and pseudoephedrine (which you need to purchase from behind the ...Sep 13, 2023 · The federal purchase limit is 3.6 milligrams of pseudoephedrine base in a single day and nine milligrams in a single month. The monthly limit should be enough to keep you covered during allergy ... The amount of fluids infused during the study period in the phenylephrine and norepinephrine groups was similar (2,554 ± 1,140 ml versus 2,431 ± 1,010 ml, P = 0.751). Phenylephrine dosages were higher than those for norepinephrine 12 hours after randomization (P < 0.001) (Figure (Figure2). 2). The goal MAP of 65 to 75 mmHg was …I have a few theories that may explain why: The drug would exist already in solution, which might make it easier to separate from inactive ingredients. This would benefit those attempting to produce methamphetamine. The drug itself may damage parts of the nose. It may simply not be very bioavailable intranasally.A warning about stimulants and cold medicine. In a nutshell, I was on 10 of Prozac titrating up to 20 slowly, and had just increased my dose of Vyvanse again when my asthma flaired up. I had to take my Albuterol inhaler and Robitussin with dextromethorphan and guaifenesin. I had a nightmare response that caused a crazy panic episode that lasted ...View community ranking In the Top 1% of largest communi, Interestingly, this is largely attributed to the meth con, Phenylephrine, the nasal decongestant in many cold medicine, Depending if it’s a dry cough or productive. Productive I’ll recommend o, Fascinating story behind that. Guaifenesin was an unapproved drug not long ago. Was in common use before the FDA came , View community ranking In the Top 1% of largest communit, According to Healthline, the phenylephrine in Prepar, Phenylephrine is an alpha-agonist - that is, it works, I personally think phenylephrine is a placebo. So many, Technically you could convert a steak into methamph, I have a few theories that may explain why: The drug would exist, Phenylephrine, the nasal decongestant in many cold, tripped on this dose years ago, im not sure if it was th, 4 oct. 2023 ... ... Reddit Print Story Like. An advisory panel to , Confusingly, popular cold remedy Sudafed – which takes its name fro, I suffer from hay fever during summer and usually take piriton , This pill contains the active ingredients Guaifenesin , Location. belly of the beast, MA. Feb 14, 2011. #1.